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Progressive Multiple Sclerosis

PHASE 1/2

Case Studies

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Key Takeaways

BBK Worldwide was engaged to support the enrollment of patients with progressive multiple sclerosis — primary progressive multiple sclerosis (PPMS) or secondary progressive multiple sclerosis (SPMS) — for a two-part study evaluating an investigational treatment. Part one was enrolling 25 patients; part two was enrolling 200 patients.

BBK was engaged to support enrollment at five of the 35 study sites.

BBK developed a robust digital advertising campaign with pre-screening optimization. 

MS doesn't take a break.

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Facebook was the top-performing outreach tactic, exceeding referral expectations within a eight-month advertising window. 

Challenges

  • The risk of ad saturation was high due to the limited number of markets (five).

  • A high anticipated screen-fail rate.

  • Enrollment for part one was limited to men and women ages 18-65; enrollment for part two was limited to men and women ages 18-60.

  • During the recruitment effort, Facebook announced that it would begin removing ad-targeting features for “sensitive” topics such as clinical trial recruitment, limiting opportunities to interest potential study participants.

Multiple Sclerosis Case Study Example

 

Solutions and Impact

BBK ran a digital advertising campaign, targeting men and women ages 40–60 years old.

 

Facebook advertising resulted in the largest number of qualified referrals, accounting for 66 percent of all referrals generated.

 

BBK optimized the online prescreener — prioritizing the patient’s knowledge of their condition, their medication history, and their willingness to provide medical records to study sites — to ensure that sites would receive quality referrals.

 

Secondary prescreening at the call center reduced the number of non-viable referrals. Outreach to referrals within 24 hours of their initial assignment increased connection rates and reduced the chances that referrals were lost to follow up.

Progressive Multiple Sclerosis

  • Sites_ICON 5 Number of study sites supported by BBK.

  • Participants_ICON 152 Referrals generated by the advertising campaign.

  • Funnel-icon 66% Percentage of referrals generated by Facebook advertising.

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