Case Study — Overactive Bladder — Urology

Key Takeaways

BBK Worldwide was hired to support patient recruitment and engagement for a large, multi-national study evaluating a new investigational combination of two approved treatments for overactive bladder (OAB) — mirabegron and solifenacin succinate. BBK had previously supported the enrollment of the phase 3 program for migabegron, helping the sponsor achieve their goal of being first-in-class to market with mirabegron.

For this enrollment effort, we needed to break through the clutter to capture patient attention with a compelling creative concept that could be culturally adapted for multiple countries.

We also needed to do a deep dive into understanding the patient audience to inform media placement for select countries.

The study included 480 sites in 45 countries and was seeking to enroll 4,250 patients.

Solutions

To resonate with the patient audience, we developed a strategy and creative concept that reflected the daily challenges that patients faced, which included bathroom mapping — a method frequently used by patients with OAB to create their daily routine based on the location of the most convenient bathrooms. The creative direction not only reflected the physical bathroom mapping, but also reflected the notion of taking action and developing a plan or strategy.

Our messaging highlighted the compelling nature of the study — two approved treatments, two distinct mechanisms of actions.

61.6% BBK’s site selection recommendations identified sites in ten countries that were responsible for 61.6% of the global screening goal, proving to be a significant source for referrals.
40 Study materials were translated and culturally adapted for 40 countries.
16 BBK achieved the enrollment goal of 4,250 patients within 16 months.