The client was struggling to enroll a clinical trial evaluating an investigational therapy for enteric hyperoxaluria in patients who had previously undergone Roux-en-Y bariatric surgery — a common cause of the condition. This was the first in-human study for the investigational therapy.
Patients are not often aware they have enteric hyperoxaluria and don’t know it is associated with painful and recurring kidney stones. So, then, how do you interest and enroll patients in a clinical trial?
Drawing on in-depth research and prior experience recruiting patients with kidney stones, BBK Worldwide leveraged a bold strategy that prioritized the very real aspect of kidney stones. BBK made the connection between bariatric surgery and kidney stones clear for patients, creating awareness and interest in the study.
Many patients are not aware of enteric hyperoxaluria and its relationship to bariatric surgery and kidney stones.
Because levels of oxalate in the kidneys fluctuate, many patients may initially prequalify for the study, only to fail the in-depth screening hours later.
BBK cast a large net by targeting patients who have had bariatric surgery and kidney stones. We leveraged Facebook, Google Search Engine Marketing, and clinical study postings, positioning the study as a potential way to treat kidney stones. We also emphasized the option of remote participation, which would appeal to this patient audience.
Dynamic referral processing was critical, as was collaboration with the CRO, to ensure that all referrals were contacted while interest was high. The effective combination of tactics and messaging resulted in 20 patients enrolled within a four-month period.
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