It’s a no brainer that applied metrics are invaluable for more accurately projecting patient recruitment; however, many people assume that once a trial is underway, it’s no longer necessary to measure anything until all the study data are accumulated. That’s just not true. There is tremendous value in the ongoing application of metrics, throughout the entire study cycle, so much so that we sometimes find it hard to imagine how anyone can conduct a successful study without metrics. But we’re not talking about numbers for numbers’ sake. It takes a great deal of expertise to know which measurements to take and how to interpret the findings.